ปัจจัยที่มีผลต่อการยอมรับวัคซีนไข้เลือดออกของผุ้ป่วยที่มารับบริการที่โรงพยาบาลแห่งหนึ่งใน จ.ยะลา

Abstract

Objective: To find factors affecting the acceptation of dengue vaccine of patients. Method: This was a cross sectional study using questionnaire to collect data from 400 patients who came to the outpatient department in one community hospital. The questionnaire consists of 4 parts: 1. General information 2. Attitude about dengue fever 3. Attitude about dengue vaccine and 4. Dengue Vaccine acceptance. Inclusion criteria: 1. Age 18-45 years old 2. They understand both speaking and listening in Thai. and3. Willing to participate in research. Exclusion criteria: 1. Immune deficiency, that cannot be vaccinated, such as HIV-infected people, cancer patients, autoimmune diseases (systemic lupus erythematosus, SLE) 2. Chronic renal failure disease 3. Genetic disorders and 4. Use of high dose steroids. Factors affecting acceptance of dengue vaccine were analyzed by Binary logistic regression. Results: Most of the samples were female (93.75%), average age 32.51 years, median of monthly income 4,500 baht. Majority (84.50%) had no experience of dengue virus infection. An acceptance of dengue vaccine was 95.00%, median of willingness to pay for 3 doses of dengue vaccine was 550 baht (min 0 baht, max 4,500 baht). There were 6 samples who do not wish to pay for dengue vaccine. Three factors significantly affecting dengue vaccine acceptance were vaccination services is free (OR=35.93, 95% CI: 10.82-119.31, P<0.001), the severity of Dengue fever (OR=7.75, 95% CI: 1.93-31.02, P=0.004) and influence from family members (OR=4.76, 95% CI: 1.26-18.02, P=0.022) The first 3 factors have resulted in increased acceptance of dengue vaccines. But the influence from family members has reduced the acceptance of dengue vaccine. Conclusion: Three factors affecting the acceptance of dengue vaccine were: free vaccine, the severity of Dengue fever and influences from family members.