ปัจจัยทำนายการยึดติดในการรักษาด้วยยาของผู้ป่วยโรคอารมณ์แปรปรวนสองขั้ว

Abstract

This predictive research aimed to study the level of medication adherence and factors predicting medication adherence among bipolar disorder patients. The sample comprised 90 bipolar disorder patients, aged 18-60 years, who had been diagnosed with bipolar disorder from ICD-10 (F31.0-31.9) and were receiving treatment at the outpatient department in Songkhla Rajanagarindra Psychiatric Hospital, southern Thailand. The research instruments consisted of 6 parts: (1) demographic data of patients with bipolar disorder, (2) medication adherence of patients with bipolar disorder scale, (3) Brief Bipolar Disorder Symptom Scale: BDSS, (4) Drug Attitude Inventory: DAI-10, (5) side effect rating scale, and (6) patient and the health care team relationship scale. The content validity of the instruments was verified by three experts. The content validity index of part 2 was 1.00. The reliability of parts 2, 5, and 6, was tested using Cronbach’s alpha coefficient, yielding values of .73, .94 and .95 respectively. The reliability of part 3 was tested using Interrater reliability, yielding a value of .80. The reliability of part 4 was tested using Kuder-Richardson 20, yielding a value of .91. Data were analyzed using descriptive statistics. The predictability was analyzed using standard multiple regression analysis (Enter Method). The result showed that medication adherence among bipolar disorder patients was at a high level (M = 63.96, SD = 6.628). Predictive factors could explain 12.2 percent of the variance (R² = .122, p< .05) For consideration, the factors that significantly predicted medication adherence were the patient and the health care team relationship (ß = .239, p< .05) and side effects of medication (ß = -.213, p< .05). The results of this study could be used as basic information to develop nursing programs to promote the development of a model of care for Bipolar Disorder Patients to enhance medication adherence.