ความสัมพันธ์ของความดันโลหิต ความแข็งตัวของหลอดเลือดแดงความแปรปรวนของอัตราการเต้นของหัวใจ และมาลอนไดอัลดีไฮด์ในคนไทยสูงอายุ

Abstract

Blood pressure assessment is an integral part of standardizing clinical practice, assessing for routine health checkups. The association of blood pressure and arterial stiffness, the autonomic nervous system activity and oxidative stress in the elderly are still unclear. This study aimed to assess the relationship between blood pressure with cardio-ankle vascular index (CAVI), heart rate variability (HRV) and malondialdehyde. A total of 103 subjects male and female; aged 60-80 years (mean age 66.06 ± 4.56 years). Systolic blood pressure and diastolic blood pressure showed a positive correlation with cardio-ankle vascular index (P < 0.05). We found a negative correlation with time domain (SDNN RMSSD and PNN50) and frequency domain parameters (LF and HF) (P< 0.05). In addition, this study showed systolic blood pressure positive correlation with plasma MDA (P < 0.05). These findings suggest that blood pressure can provide an enhanced diagnosis index, and possibly prognostic information regarding arterial stiffness, heart rate variability and malondialdehyde that help reduce cardiovascular disease mortality.