ผลของซิลเวอร์ไดเอมีนฟลูออไรด์ต่อความแข็งจุลภาคและความหนาแน่นแร่ธาตุในรอยผุจำลองชั้นเนื้อฟันภายใต้วงจรเปลี่ยนแปลงความเป็นกรด-ด่าง ที่ต่างกัน

Abstract

Objective: To study the effect of 38% SDF application in difference pHcycling models, on the microhardness and mineral density in artificial carious dentine. Methods: The sample was 120 specimens from sound premolar teeth induced to artificial carious dentine and allocated to 6 groups: 38% SDF 1 time, 3 times, and no application; under 2 pH-cycling models: long and short-time acid exposure (16 hours / day and 1 hour x 3 times / day in order). The cross-sectional microhardness and mineral density were test. Each group used 10 samples per each test (n=10) Results: When comparing only the four experimental groups tested which the test were done on the seventh day of the experiment, the application of SDF in a short-time acid exposure model resulted in the greatest increase in mineral density. However, the microhardness was not different from that of the SDF long-time acid exposure model group, and from the descriptive statistic, results showed that 3 time-application of SDF had higher mineral density than the initial. But only at 3 time-application in the long-time acid exposure model which the test was done on the 21 days of the experiment, the microhardness was greatly reduced. Conclusion: The pH-cycling model and SDF application were factors that resulted in the increase in microhardness and mineral density from the beginning. It was found that the short-time acid exposure model with SDF application showed the best results and the repeated application of SDF had increased mineral density and microhardness from the initiate. Whereas in the long-time acid exposure model with multiple application of SDF had been shown to increase the mineral density but may not increase the microhardness.