PSU Knowledge Bank Collection:
http://kb.psu.ac.th:80/psukb/handle/2010/5532
2024-03-28T12:30:11Zผลของซิลเวอร์ไดเอมีนฟลูออไรด์ต่อความแข็งจุลภาคและความหนาแน่นแร่ธาตุในรอยผุจำลองชั้นเนื้อฟันภายใต้วงจรเปลี่ยนแปลงความเป็นกรด-ด่าง ที่ต่างกัน
http://kb.psu.ac.th:80/psukb/handle/2016/18036
Title: ผลของซิลเวอร์ไดเอมีนฟลูออไรด์ต่อความแข็งจุลภาคและความหนาแน่นแร่ธาตุในรอยผุจำลองชั้นเนื้อฟันภายใต้วงจรเปลี่ยนแปลงความเป็นกรด-ด่าง ที่ต่างกัน
Authors: อัณณ์ศรา ชิณโชติ
Abstract: Objective: To study the effect of 38% SDF application in difference pHcycling models, on the microhardness and mineral density in artificial carious dentine. Methods: The sample was 120 specimens from sound premolar teeth induced to artificial carious dentine and allocated to 6 groups: 38% SDF 1 time, 3 times, and no application; under 2 pH-cycling models: long and short-time acid exposure (16 hours / day and 1 hour x 3 times / day in order). The cross-sectional microhardness and mineral density were test. Each group used 10 samples per each test (n=10) Results: When comparing only the four experimental groups tested which the test were done on the seventh day of the experiment, the application of SDF in a short-time acid exposure model resulted in the greatest increase in mineral density. However, the microhardness was not different from that of the SDF long-time acid exposure model group, and from the descriptive statistic, results showed that 3 time-application of SDF had higher mineral density than the initial. But only at 3 time-application in the long-time acid exposure model which the test was done on the 21 days of the experiment, the microhardness was greatly reduced. Conclusion: The pH-cycling model and SDF application were factors that resulted in the increase in microhardness and mineral density from the beginning. It was found that the short-time acid exposure model with SDF application showed the best results and the repeated application of SDF had increased mineral density and microhardness from the initiate. Whereas in the long-time acid exposure model with multiple application of SDF had been shown to increase the mineral density but may not increase the microhardness.
Description: วิทยาศาสตรมหาบัณฑิต (วิทยาศาสตร์สุขภาพช่องปาก), 25642021-01-01T00:00:00Zผลของระยะเวลาที่ใช้ในการทาซิลเวอร์ไดเอมีนฟลูออไรด์ต่อความแข็งแรงยึดเฉือนของเนื้อฟันที่มีการสลายแร่ธาตุกับวัสดุกลาสไอโอโนเมอร์ ซีเมนต์: การศึกษานอกร่างกาย
http://kb.psu.ac.th:80/psukb/handle/2016/17897
Title: ผลของระยะเวลาที่ใช้ในการทาซิลเวอร์ไดเอมีนฟลูออไรด์ต่อความแข็งแรงยึดเฉือนของเนื้อฟันที่มีการสลายแร่ธาตุกับวัสดุกลาสไอโอโนเมอร์ ซีเมนต์: การศึกษานอกร่างกาย
Authors: มัณฑนาภรณ์ กรอุไร
Abstract: Objective: The aim of this in vitro study was to assesses the effect of application times of SDF on the bond between glass ionomer cement and the dentin of primary teeth. Methods: Forty-eight dentin specimens were prepared from the extracted primary teeth. Artificial dentin carious lesions were created by a pH-cycling procedure. All of specimens were divided into four groups (n=12/group); Group 1 apply with deionized water, Group 2, 3 and 4 apply SDF 10, 30 and 60 seconds, respectively. After that, glass ionomer cement (Fuji IX GP extra) was bonded onto specimens and stored in deionized water. After 48 hours, the specimens (N=11/group) were prepared for shear bond strength testing and the failure mode was assessed with a 3D-profilometer. One specimen from each group were prepared for mineral density and penetration depth assessment using micro-CT µ35 and scanning electron microscope (SEM QUANTA). Results: In relation to the shear bond strength effect, no statistically significant differences were observed among the groups (p=0.66). The shear bond strength (mean±SD) after treatment with deionized water, 10 seconds SDF, 30 seconds SDF and 60 seconds SDF were 2.39 ± 1.36 MPa, 2.51 ± 1.00 MPa, 2.95 ± 0.99 MPa and 2.47 ± 1.12 MPa, respectively. Most common failure mode was the mixed failure mode in all groups. The dentin mineral density was increased in the SDF groups. The penetration depth of silver ion into dentinal tubule was upto 1,000 µm. in all SDF groups. Conclusion: The bond strength between glass ionomer cement and demineralized primary dentin and the penetration depth of silver ion into dentinal tubule have been neither affected by the application of silver diamine fluoride nor the various of application times.
Description: วิทยาศาสตรมหาบัณฑิต (สาขาวิชาวิทยาศาสตร์สุขภาพช่องปาก).25652022-01-01T00:00:00ZEffects of Parental Migration and the Caregiver’s Response to Health Advice on Oral Health of 6-to-8 Years Old Rural Children: A Cross-Sectional with Short Follow-up Study
http://kb.psu.ac.th:80/psukb/handle/2016/17854
Title: Effects of Parental Migration and the Caregiver’s Response to Health Advice on Oral Health of 6-to-8 Years Old Rural Children: A Cross-Sectional with Short Follow-up Study
Authors: Liu, Sichen
Abstract: Background
International and internal parental migration have been steadily increased with urbanization and globalization. Children with parental migration are called "left-behind children (LBC)". Parental migration has been shown to have a negative effect on the children's health and oral health. No studies have explored the complex association between parental migration and dental caries in children and examined the responses to professional advice on oral health care between caregivers of left-behind children (LBC) and non-left-behind children (NLBC). Understanding those will help policymakers develop a specific and effective policy and improve the healthcare services for left-behind children.
Objectives
The objectives of this study were 1) to compare the oral health behaviours between the 6-8-year-old children with different parental migration duration; 2) to investigate whether parental migration is associated with dental caries among 6-8-year-old children, and 3) to compare the responses to the dental professional advice of the caregivers of LBC and NLBC.
Methods
There were 2 parts to the study. Part I aims to answer objectives 1 and 2 and was the cross-sectional study. Moreover, Part II was a prospective cohort study for objective 3. This study population was children aged 6-8 years old. The sample size was calculated with a 5% replacement for the non-response total getting at least 466 children. It was conducted in 7 primary schools in three rural counties in Yunnan, China. The multi-level stratified cluster sampling was used to select the samples. The questionnaires were modified from the 4th National Oral Epidemiological Survey in China. Part I, the caregivers of all children were interviewed using structural questionnaire on demo-socioeconomic characteristics, children's oral health behaviours, and oral health care utilization. An oral health examination based on the criteria of the WHO oral health survey was conducted on children. The advice was given to caregivers after an oral health examination. After 2-3 months, the questionnaire regarding response to advice for self-care and professional care and the reasons were collected from the caregivers.
The weighted descriptive statistics were used to estimate a representative oral health situation among the targeted population accounting for the cluster of the studied samples. A Chi-square test for survey data was used to compare the difference in outcome variables among parental migration durations. A Chi-squared test for trend in proportions for weighted proportions was performed to test a linear trend between dental caries and parental migration durations. The effect of parental migration on dental caries in children was analyzed by Structural Equation Modelling (SEM) to investigate the complex relationships between the exposures and outcomes as well as their mediators and confounders.
Results
Data were collected from 500 Chinese children aged 6-8-year-old with their caregivers. There were 191 children without parental migration (38.2%), 50 children with parental migration of less than 6 months (10%), 87 children with parental migration of 6 to 12 months (17.4%), and 172 children with parental migration of more than 12 months (34.4%). Primary caregivers of children with parental migration were more likely to be mothers or non-parents, had older ages, had lower than elementary school, and had no jobs. This study found a high prevalence and number of total caries (91.6% and 7.53 ± 4.27, respectively). The univariable analysis showed no significant differences in frequency of toothbrushing, fluoride toothpaste, dental attendance, and the number of dental caries (p > 0.05) but significant difference in the frequency of snacking consumption between different parental migration durations (p < 0.02). In addition, there was a statistically significant linear increase in caries prevalence in the primary teeth (dft) and total caries (DMFT + dft) with increased parental migration durations (p < 0.05).
The SEM showed that after controlling for the socioeconomic status of the caregiver, there was an association between parental migration and dental caries in number of permanent teeth in the children through snack consumption. Longer parental migration duration and non-parental or single parent caregivers increased the snack frequency of the children, and consequently increased the risk of dental caries in number of permanent teeth.
In part II, 389 children with their caregivers participated. It consisted of 183 NLBC (47%) with No or < 6 months of parental migration and 206 LBC (53.0%) with ≥ 6 months of parental migration. Significantly, more NLBC's than LBC's caregivers supervised their children for daily oral health behaviours or self-care (p < 0.04). About one-third of the caregivers took their children to visit the dentist after getting professional advice. There was no significant difference in response to the advice for professional care between LBC and NLBC's caregivers. The main reason for not bringing children to visit dentists was that caregivers thought that dental disease was not severe and the child had no pain. These reflected no concern about their children's oral health among most caregivers.
Conclusions
This study demonstrated that after controlling for SES, parental migration increases dental caries in number of permanent teeth in children through snacking frequency. Caregivers had good compliance with self-care or supervising children's daily oral health behaviours, but not professional care or bringing children to the dental clinic. There is a need to develop the policy and oral health promotion programs specific to the children and caregivers in parental migration families. More oral health education should provide to all caregivers in the rural families to raise oral health knowledge and awareness. Interdisciplinary cooperation research should conduct in this group to understand the impact of parental migration on children's health, oral health, and well-being.
Description: Thesis (Ph.D., Oral Health Sciences)--Prince of Songkla University, 20222022-01-01T00:00:00ZEffects of Compressive Stress Combined with Mechanical Vibration on Osteoclastogenesis of RAW 264.7 Cells
http://kb.psu.ac.th:80/psukb/handle/2016/17842
Title: Effects of Compressive Stress Combined with Mechanical Vibration on Osteoclastogenesis of RAW 264.7 Cells
Authors: Boontida Changkhaokham
Abstract: The effects of mechanical stimulation on osteoclastic differentiation differ depending on the pattern of mechanical loading. However, there is still no knowledge about mechanical vibration combination with compressive force applied on osteoclast precursor cells. Objectives This study purposed to investigate the effects of compressive force combined with mechanical vibration or mechanical vibration alone on osteoclastogenesis in RAW 264.7 cells, a murine osteoclastic-like cell line. Materials and Methods Murine monocyte/macrophage RAW 264.7 cells were used as model osteoclast precursor cells. To determine the optimal compressive force and mechanical vibration. Various compressive force (0.3, 0.6 or 0.9 g/cm2) was applied to RAW 264.7 cells and induced with either 30 Hz or 60 Hz at 0.49 g. To determine the effects of compressive force combination with mechanical vibration, RAW 264.7 cells were subjected to suitable compressive force or mechanical vibration for 20 min every 24 h for 4 days or combination of compressive force and vibration. Cell viability was assessed using Prestoblue assay. NFATc1, DC-STAMP and CTSK gene expression were measured by quantitative realtime reverse transcription polymerase chain reaction (RT-PCR) and the numbers of TRAP-positive multinucleated cells (MNCs) were counted and analyzed Results: Compressive force combination with mechanical vibration significantly increased the numbers of TRAP-positive multinucleated cells when compared with compressed or vibrated group (P<0.05). Application of force on RAW 264.7 cells did not significantly affect cell viability. The combination of compressive force and vibration significantly increased NFATc1, DC-STAMP, and CTSK mRNA expression, compared to compressive force or vibration alone (P<0.05). Conclusions: Compressive force combined with mechanical vibration induces osteoclastogenesis and upregulates the expression of NFATc1, DC-STAMP and CTSK gene on RAW 264.7 cells. These results provide more insight into the mechanisms by which vibratory force accelerates orthodontic tooth movement.
Description: Thesis (Ph.D., Oral Health Sciences)--Prince of Songkla University, 20222022-01-01T00:00:00Z